Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects

ALS Motor Neurons Differ by Sex, Study Finds. A new Cedars-Sinai study in collaboration with the University of California, Irvine (UCI) and the Answer ALS consortium has examined the expression of thousands of genes in stem cell-generated motor neurons that are known to die in patients with ALS.

The study, published in the peer-reviewed journal Neuron, revealed sex was one of the main drivers of different gene expression in motor neurons, regardless of whether they were from patients diagnosed with ALS or controls. Read the entire study here: http://bit.ly/3J6yldG