Answer ALS holds the largest ALS patient data resource in the world, and it is helping aspiring young scientists get their start. They come to Answer ALS drawn by the science, sometimes for personal reasons, and Answer ALS is giving them the mentorship, the scientific guidance, and the data required to take on their first…
When Mrigank Pandey began examining the biological mechanics of Amyotrophic Lateral Sclerosis (ALS), he found two numbers that stood out to him. The first was 12 months, which was the amount of time it took for a family friend’s aunt to decline and pass away after her diagnosis. The second was 55 years, the length…
In their senior year at Thomas Jefferson High School for Science and Technology in Northern Virginia, Ashwitha Surabhi and her project partner settled on a computational research project in the school’s neuroscience lab, intending to train a machine learning model to predict ALS symptoms early and classify frontotemporal dementia. Most of the comprehensive biomarker datasets…
Institutions love silos; revolutions love transparency. For generations, medical research operated under its own kind of feudalism, where laboratories functioned like closed fiefdoms, guarding discoveries behind proprietary gates and expensive paywalls. In 2014, Steve Gleason, a former professional football player living with amyotrophic lateral sclerosis, decided to challenge that entrenched complacency. He convened a historic…
Moonshine Flats is a country bar in San Diego’s Gaslamp Quarter, the kind of place that books live bands on Saturday nights and pours copious amounts of bourbon for tourists. On March 9 it served a different purpose altogether. Nearly 100 members of the aviation community filled the venue during the International Society of Transport…
Magic usually involves smoke and mirrors, but the researchers filling the Four Seasons Hotel ballroom in Baltimore for Answer ALS’s “IgNight: Where the Magic of Collaboration Meets the Power of Science” on March 1 proved that the most impressive tricks involve data, cloud computing, artificial intelligence, and scientists who won’t take impossible for an answer….
Ambitious nationwide study will enroll 500 participants to examine genetic, biological, and environmental factors linked to elevated ALS risk. NEW ORLEANS, February 4, 2026 — Champion Insights officially commenced active research operations today in its nationwide study investigating why elite athletes, military veterans, and high-performance populations, like first responders, face disproportionately high rates — potentially up…
Platform tennis prioritizes aggression. It is a sweat-covered game played inside a wire cage while winter winds cut across the aluminum decking. Jim Marvel knows this dynamic better than anyone. He serves as a key organizer for the region and frequently directs major events like the Kansas City Open Men’s National Ranking Tournament. He understands…
A digital holiday card of gratitude. Many thanks and Happy Holidays to all.
On December 11, AALS presented a live demo and tutorial of the Neuromine Data Portal. This webinar showed researchers, clinicians, and data scientists how to harness ALS’s most comprehensive open-access data resource (over 150+ TB of multiomics and clinical data from more than 2,500 patients). Supported and maintained by the Answer ALS Foundation, Neuromine brings…
All data from 1,100+ Answer ALS participants, including ALS TDI’s ARC study data, are now harmonized and accessible via the Neuromine Data Portal, forming the world’s largest open ALS research resource to accelerate discoveries. NEW ORLEANS, November 03, 2025 — Answer ALS today announced the full release of its comprehensive ALS clinical and multi-omics dataset,…
NEW ORLEANS, La. [February 2025]: Answer ALS co-hosted the Game Changer Gala with Team Gleason during Super Bowl LIX week, bringing together leaders from sports, technology, research, philanthropy, and the arts to raise support for ALS research and patient empowerment. The Gala took place at the Mardi Gras World Float Den Annex and celebrated the…
Data & TechnologyHarnessing Big Data with Advanced Analytics Neuromine is one of the world’s most robust and comprehensive ALS data resources, integrating multi-omics, clinical, and cellular datasets, while also linking to coordinating iPSC lines, biosamples, and other large-scale data platforms with analytic tools to maximize discovery and collaboration.
Multi-Omnics AnalysisComprehensive Biological Data Integration Making a comprehensive multi-omics datasets available that integrates genomics, transcriptomics, proteomics, epigenomics, and iPSC-derived motor neuron data that is freely accessible for analysis.
IPS Cells & Motor NeuronsGenerated 1,000 Participant-Derived Cell Lines Learn More about how to access 1,000 iPSC lines through our partners at the Cedars-Sinai Biomanufacturing Center
Clinic & enrollmentLeading Clinics Engaged to Complete Enrollment Enrollment in the Answer ALS program is complete, but you can Learn More about connected programs like Champion Insights, ALS Therapy Development’s ARC Program
