All data from 1,100+ Answer ALS participants, including ALS TDI’s ARC study data, are now harmonized and accessible via the Neuromine Data Portal, forming the world’s largest open ALS research resource to accelerate discoveries. NEW ORLEANS, November 03, 2025 — Answer ALS today announced the full release of its comprehensive ALS clinical and multi-omics dataset,…
State-of-the-art remote-participation research seeks to understand how genetic factors linked to intense activities and lipid metabolism may increase ALS susceptibility NEW ORLEANS, August 13, 2025 — Answer ALS, in collaboration with ALS Therapy Development Institute (ALS TDI) and Augie’s Quest, today announced plans to launch Champion Insights, an ambitious research initiative designed to uncover critical…
NEW ORLEANS, July 22, 2025 — Answer ALS is proud to announce the launch of a groundbreaking collaborative initiative aimed at accelerating AI-powered drug discovery for ALS and other neurodegenerative diseases. This effort, known as the Louisiana AI Drug Development Infrastructure for ALS (LADDIA), brings together leading institutions and innovators, including GATC Health — a…
Terri Thompson’s Multidisciplinary Approach Terri Thompson didn’t set out to work in ALS research. She had been working on a data-sharing platform for NASA, helping make research from spaceflight experiments easier for scientists to access and use. That experience opened the door to new collaborations, and eventually she was invited to join a group of…
Answer ALS is deeply alarmed and disappointed by Congress’ passage of the Full-Year Continuing Appropriations Act, which includes devastating cuts to ALS research funding. For years, funding for ALS research has grown steadily thanks to bipartisan support and the tireless efforts of the ALS community. These hard-fought increases have fueled groundbreaking progress in understanding ALS,…
Integrated data sharing platforms to accelerate research into ALS and Alzheimer’s disease by providing access to collaborative tools and datasets
Unprecedented resource, created with Cedars-Sinai, to accelerate ALS research and drive development of targeted therapies globally
The ALS Therapy Development Institute (ALS TDI), Answer ALS, and Microsoft are pleased to announce a collaboration that will bring together the two largest existing clinical and omics data sets relating to ALS. Through this partnership, comprehensive data collected through ALS TDI’s ALS Research Collaborative (ARC) will be added to Neuromine, an innovative data portal…
Dr. Jeffrey Keller to Co-Lead Answer ALS’ Unprecedented Open Access ALS Data Repository. Appointment to Answer ALS bridges revolutionary data repository with renowned biomedical research center. NEW ORLEANS, Louisiana—Answer ALS is excited to announce that Dr. Jeffrey Keller, Ph.D. has been selected as Answer ALS’ Principal Investigator over the program’s renowned open-access data repository, Neuromine….
10 Years of Commitments Met. Ten years ago, Answer ALS didn’t have a name, but the plan was developed to empower researchers around the world to help bring an end to ALS. In the video below, created when the program first began, every commitment made has been or is being met. Through a massive coordination…
Our 2022 4th quarter newsletter is available here. There has been a lot to celebrate, but there is so much more work to do. Please read about what the researchers supporting and utilizing Answer ALS samples and data have been working on to bring an end to the disease. https://conta.cc/3X0cjgZ
ALS Motor Neurons Differ by Sex, Study Finds. A new Cedars-Sinai study in collaboration with the University of California, Irvine (UCI) and the Answer ALS consortium has examined the expression of thousands of genes in stem cell-generated motor neurons that are known to die in patients with ALS. The study, published in the peer-reviewed journal…
Data & TechnologyHarnessing Big Data with Advanced Analytics Neuromine is one of the world’s most robust and comprehensive ALS data resources, integrating multi-omics, clinical, and cellular datasets, while also linking to coordinating iPSC lines, biosamples, and other large-scale data platforms with analytic tools to maximize discovery and collaboration.
Multi-Omnics AnalysisComprehensive Biological Data Integration Making a comprehensive multi-omics datasets available that integrates genomics, transcriptomics, proteomics, epigenomics, and iPSC-derived motor neuron data that is freely accessible for analysis.
IPS Cells & Motor NeuronsGenerated 1,000 Participant-Derived Cell Lines Learn More about how to access 1,000 iPSC lines through our partners at the Cedars-Sinai Biomanufacturing Center
Clinic & enrollmentLeading Clinics Engaged to Complete Enrollment Enrollment in the Answer ALS program is complete, but you can Learn More about connected programs like Champion Insights, ALS Therapy Development’s ARC Program
